Welcome to the Shavit Laboratory at the University of Michigan. We study the genetics of human blood clotting disorders using zebrafish and mouse models. We are developing large scale zebrafish mutagenesis screens to identify genetic and chemical modifiers of these disorders. This will be followed by investigation of these modifiers in mouse models and human populations.
Our laboratory is a member of the Department of Pediatrics and Communicable Diseases, Comprehensive Cancer Center, and Cardiovascular Center.