Publications

The Shavit Laboratory
    1. Kretz CA, Weyand, AC and Shavit JA. Modeling disorders of blood coagulation in the zebrafish. Curr Pathobiol Rep, 3:155-161, 2015.
    2. Huarng, MC and Shavit JA. Simple and rapid quantification of thrombocytes in zebrafish larvae. Zebrafish, 12:238-42, 2015.
    3. Weyand, AC and Shavit JA. Zebrafish as a model system for the study of hemostasis and thrombosis. Curr Opin Hematol, 21:418-22, 2014.
    4. Liu Y, Kretz CA, Maeder ML, Richter CE, Tsao P, Vo AH, Huarng, MC, Rode T, Hu Z, Mehra R, Olson ST, Joung JK, and Shavit JA. Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function, Blood, 124:142-50, 2014.
    5. Dang, LT, Shavit JA, Singh, RK, Joshi SM, Leber SM, Barks, JD, and Shellhaas RA. Subdural hemorrhages associated with antithrombotic therapy in infants with cerebral atrophy, Pediatrics, 134(3):e889-93, 2014.
    6. Raeker M.O., Shavit JA, Dowling JJ, Michele DE, and Russell MW. Membrane-myofibril cross-talk in myofibrillogenesis: lessons from the zebrafish, Front Physiol, 5:14, 2014.
    7. Vo A, Swaroop A, Liu Y, Norris ZG, and Shavit JA. Loss of fibrinogen in zebrafish results in symptoms consistent with human hypofibrinogenemia, PLOS One, 8:e74682, 2013.
    8. Desch KC, Ozel AB, Siemieniak D, Kalish Y, Shavit JA, Thornburg CD, Sharathkumar AA, McHugh CP, Laurie CC, Crenshaw A, Mirel DB, Kim Y, Cropp CD, Molloy AM, Kirke PN, Bailey-Wilson JE, Wilson AF, Mills JL, Scott JM, Brody LC, Li JZ, and Ginsburg D. Linkage analysis identifies a novel locus for plasma von Willebrand factor undetected by genome-wide association. Proc Natl Acad Sci USA, 110:588-93, 2013.
    9. Ghosh A, Vo A, Twiss BK, Kretz CA, Jozwiak MA, Montgomery RR, and Shavit JA. Characterization of zebrafish von Willebrand factor reveals conservation of domain structure, multimerization, and intracellular storage. Adv Hematol, 2012:1-9, 2012.
    10. Shavit JA. The bleeding edge of symptom assessment. Pediatr Blood Cancer, 58:657-8, 2012.
    11. 17. Chen X, Leto D, Xiao J, Goss J, Wang Q, Shavit JA, Xiong T, Yu G, Ginsburg D, Toomre D, Xu Z, and Saltiel AR. The function of the exocyst is regulated by effector phosphorylation. Nat Cell Biol, 13:580-8, 2011.
    12. Peters LL, Shavit JA, Lambert AJ, Tsaih S, Li Q, Su Z, Leduc MS, Paigen B, Churchill, GA, Ginsburg D, and Brugnara C. Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood, 116:e139-49, 2010.
    13. Shavit JA, Manichaikul, A, Lemmerhirt HL, Broman KW, and Ginsburg D. Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice. Blood, 114:5368-74, 2009.
    14. Su F, Juarez MA, Cooke CL, LaPointe L, Shavit JA, Yamaoka JS, and Lyons SE. Differential regulation of primitive myelopoiesis in the zebrafish by Spi-1/Pu.1 and C/ebp1. Zebrafish, 4:187-99, 2007.
    15. Buchner DA, Su F, Yamaoka JS, Kamei M, Shavit JA, Barthel LK, McGee B, Amigo JD, Kim S, Hanosh AW, Jagadeeswaran P, Goldman D, Lawson ND, Raymond PA, Weinstein BM, Ginsburg D, and Lyons SE. pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proc Natl Acad Sci USA, 104:13996-14001, 2007.
    16. Lemmerhirt HL, Broman KW, Shavit JA, and Ginsburg D. Genetic regulation of plasma von Willebrand factor levels: QTL analysis in a mouse model. J Thromb Haemost 5:329-35, 2007.
    17. Lemmerhirt HL, Shavit JA, Levy GG, Cole SM, Long JC, and Ginsburg D. Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene. Blood 108:3061-7, 2006.
    18. Shavit JA and Motto DG. Coagulation and metastasis – an unexpected role for von Willebrand factor. J Thromb Haemost 4:517-8, 2006.
    19. Cheatham MA, Pearce M, Richter CP, Onodera K, and Shavit JA. Use of the pinna reflex as a test of hearing in mutant mice. Audiol Neuro-Otol 6:79-86, 2001.
    20. Motohashi H, Katsuoka F, Shavit JA, Engel JD, and Yamamoto M. Positive or negative MARE-dependent transcriptional regulation determined by the abundance of small Maf proteins. Cell 103:865-75, 2000.
    21. *Onodera K, *Shavit JA, *Motohashi H, Yamamoto M, and Engel JD. Perinatal synthetic lethality and hematopoietic defects in compound mafG::mafK mutant mice. EMBO J 19:1335-45, 2000.
    22. Onodera K, Shavit JA, Motohashi H, Katsuoka F, Akasaka J, Engel JD, and Yamamoto M. Characterization of the murine mafF gene. J Biol Chem 274:21162-9, 1999.
    23. Shavit JA and Engel JD. Regulation of megakaryopoiesis and neurogenesis by the proto-oncogene, mafG. J Lurie Cancer Center 6:23-30, 1999.
    24. Shavit JA, Motohashi H., Onodera K, Akasaka J, Yamamoto M., and Engel JD. Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. Genes Dev 12:2164-74, 1998.
    25. *Motohashi H, *Shavit JA, Igarashi K, Yamamoto M, and Engel JD. The world according to Maf. Nuc Acids Res 25:2953-60, 1997.
    26. Bungert J, Davé U, Lim K-C, Lieuw KH, Shavit JA, Liu Q, and Engel JD. Synergistic regulation of human -globin gene switching by locus control region elements HS3 and HS4. Genes Dev 9:3083-96, 1995.
    27. Iyer L, Shavit J, Koza M, Calabria R, Moran S, and Fareed J. Alteration of pharmacokinetics and pharmacodynamics of hirudin (rHV2-Lys 47) after repeated intravenous administration in dogs. Thromb Res 69:59-70, 1993.

      *co-first authors

Start typing and press Enter to search